Hypermobility Spectrum Disorder can lead to which of the following?

Hypermobility Spectrum Disorder can lead to which of the following?

• A. Early osteoarthritis
• B. Gout
• C. Parkinson's disease
• D. Multiple sclerosis

Answer: (A)

Joint instability from Hypermobility Spectrum Disorder creates abnormal, repetitive stress on joints, leading to accelerated wear of cartilage and early degenerative changes. This mechanical pathway directly predisposes to osteoarthritis occurring sooner than in typical joints, making early osteoarthritis the most likely outcome. Gout results from uric acid crystal deposition, Parkinson's disease is a neurodegenerative condition, and multiple sclerosis is an autoimmune CNS disorder—none are direct consequences of joint hypermobility.

Joint instability from Hypermobility Spectrum Disorder creates abnormal, repetitive stress on joints, leading to accelerated wear of cartilage and early degenerative changes. This mechanical pathway directly predisposes to osteoarthritis occurring sooner than in typical joints, making early osteoarthritis the most likely outcome.

Gout results from uric acid crystal deposition, Parkinson's disease is a neurodegenerative condition, and multiple sclerosis is an autoimmune CNS disorder—none are direct consequences of joint hypermobility.