In psoriatic arthritis, rheumatoid factor is typically

In psoriatic arthritis, rheumatoid factor is typically

• A. Negative
• B. Positive
• C. Unreliable
• D. Not tested

Answer: (A)

Rheumatoid factor is typically negative in psoriatic arthritis. This condition belongs to the seronegative spondyloarthropathies, where antibodies like RF, which are often positive in rheumatoid arthritis, are usually absent. A negative RF supports the diagnosis of PsA when psoriasis and inflammatory arthritis are present, whereas a positive RF would make rheumatoid arthritis more likely. Anti-CCP antibodies are also usually negative in PsA, helping distinguish it from RA.

Rheumatoid factor is typically negative in psoriatic arthritis. This condition belongs to the seronegative spondyloarthropathies, where antibodies like RF, which are often positive in rheumatoid arthritis, are usually absent. A negative RF supports the diagnosis of PsA when psoriasis and inflammatory arthritis are present, whereas a positive RF would make rheumatoid arthritis more likely. Anti-CCP antibodies are also usually negative in PsA, helping distinguish it from RA.