Which gender is more commonly affected by Ankylosing Spondylitis?

Which gender is more commonly affected by Ankylosing Spondylitis?

• A. Females
• B. Unknown
• C. Males
• D. Both equally

Answer: (C)

Ankylosing spondylitis shows a male predominance. In most populations, far more men are affected than women, with estimates often around a 2–3:1 ratio. This difference is thought to reflect a combination of genetic and clinical factors: men more commonly have the classic radiographic sacroiliitis and axial spine involvement that defines the condition, while women may present with subtler imaging findings or more peripheral symptoms, which can delay recognition. Because of this pattern, the gender most commonly affected is male.

Ankylosing spondylitis shows a male predominance. In most populations, far more men are affected than women, with estimates often around a 2–3:1 ratio. This difference is thought to reflect a combination of genetic and clinical factors: men more commonly have the classic radiographic sacroiliitis and axial spine involvement that defines the condition, while women may present with subtler imaging findings or more peripheral symptoms, which can delay recognition. Because of this pattern, the gender most commonly affected is male.